Abstract

GARCIA MORUA, Alejandro; GUTIERREZ GARCIA, Jesús Domingo; ARRAMBIDE GUTIERREZ, José Gustavo  and  GOMEZ GUERRA, Lauro Salvador. Penile calciphylaxis: 5-year experience and literature review. Actas Urol Esp [online]. 2009, vol.33, n.9, pp.1019-1023. ISSN 0210-4806.

Introduction: Necrosis of the penis is a rare conditon that may occur as a result of infectious dissemination, circulatory disorders, or even in patients with penile prostheses. It has been reported in a few patients on dialysis, usually associated with diabetes mellitus, cholesterol embolism, and calciphylaxis. Case reports: Three patients with this condition seen at our hospital in the last 5 years are reported. Conclusions: Calciphylaxis is a rare but often fatal condition occurring in approximately 1% of patients with chronic renal failure. It is characterized by calcification of subcutaneous arteries and infarction of the subcutaneous cellular tissue and overlying skin. It is associated to a high morbidity and mortality, and diagnosis is usually based on clinical signs and symptoms. Management is controversial, particularly with regard to surgery, which may range from penectomy to local care of lesion, debridement, or antibiotic therapy.

Keywords : Calciphylaxis; Penile necrosis; Diabetes mellitus; Gangrene; Renal failure.

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