Abstract

GARCIA-ESCUDERO LOPEZ, Á. et al. Secondary amyloidosis of the bladder and massive hematuria. Actas Urol Esp [online]. 2010, vol.34, n.1, pp.111-115. ISSN 0210-4806.

Objective: To report four additional cases of secondary amyloidosis of the bladder, an extremely rare condition, as shown by the cases reported in the literature. Materials and methods: Four clinical cases are reported, all of them occurring as hematuria, which was massive and fulminant and resulted in death in three patients. Results: Secondary amyloidosis of the bladder is of the AA type, which is more common in females and mainly secondary to rheumatoid arthritis, but also to ankylosing spondylitis and long-standing chronic inflammatory conditions. Hematuria is the main and virtually only symptom. A pathological and immunohistochemical study confirmed diagnosis. All three patients who experienced massiva, fatal hematuria had an intercurrent condition requiring urethral catheterization, which was the triggering factor. Conclusions: Despite its rarity, as shown by the few cases reported, secondary amyloidosis of the bladder should be considered in patients already diagnosed with systemic amylodosis and/or the conditions reported who require simple urethral catheterization.

Keywords : Secondary amyloidosis; Urinary bladder; Massive hematuria.

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