Abstract

GONZALEZ-JIMENEZ, Emilio; MONTERO-ALONSO, Miguel A.  and  SCHMIDT-RIO VALLE, Jacqueline. C-reactive protein as a biochemical marker of cardiovascular risk. Nutr. Hosp. [online]. 2013, vol.28, n.6, pp.2182-2187. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2013.28.6.6807.

Objectives: The first objective of this study was to analyze the metabolic profile of the population to be studied. The second one was to ascertain whether there was a significant association between the nutritional status of the subjects and the serum level of C-reactive protein. Finally, the third objective was to discover whether there was a correlation between C-reactive protein serum levels and waist to hip ratio values. Sample and methodology: The sample was composed of 1001 adolescents, 9-17 years of age, from 18 schools in the provinces of Granada and Almeria. Their nutritional status was determined by means of anthropometric evaluation. For the metabolic study, a blood sample was collected from each subject by venipuncture. An analysis was performed of C-reactive protein, basal glycemia, ceruloplasmin, glycated hemoglobin (HBA1c), basal insulin, serum levels of lipoprotein (a), and non-esterified fatty acids (NEFA). Results: The biochemical study reflected a normal metabolic profile with serum levels of C-reactive protein, basal glycemia, ceruloplasmin, glycated hemoglobin, basal insulin, lipoprotein (a) and non-esterified fatty acids slightly higher in the male subjects. The results of our studied showed that there was a statistically significant association (p < 0.05; F = 3.701) between the nutritional status of the subjects and serum levels of C-reactive protein. A statistically significant association (F = 9.008; p < 0.005) was also found between serum levels of C-reac-tive protein and waist to hip ratio values. Conclusions: The C-reactive protein associated either with nutritional status or the waist to hip ratio is an effective biochemical marker of cardiovascular risk among the population of adolescents in our study.

Keywords : Nutritional status; C-reactive protein; Cardiovascular risk; Adolescents.

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