Abstract

RAVANINI, Guilherme de Andrade Gagheggi; FILHO, Pedro Eder Portari; ABRANTES LUNA, Renato  and  OLIVEIRA, Vinicius Almeida de. Organic inflammatory response to reduced preoperative fasting time, with a carbohydrate and protein enriched solution: a randomized trial. Nutr. Hosp. [online]. 2015, vol.32, n.2, pp.952-957. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.2.8944.

Background: this study aims to assess the organic inflammatory response of the video laparoscopic cholecystectomy, with abbreviation of the preoperative fasting to 2h using a carbohydrate and protein enriched solution. Methods: this is a randomized, prospective study with patients divided into the following 2 groups: group A, conventional fasting and group B, 2h abbreviated fasting with oral ingestion of a carbohydrate and protein solution. Serum glucose, insulin, interleukin 1, and TNF-α were mesasured before ingestion of the solution, during induction of anesthesia, and 4 h after the end of surgery. Results: thirty-eight patients completed the study without presenting pulmonary complications associated with bronchoaspiration. The postoperative HOMA-IR variance was greater in group A (p = 0.001). Conclusion: the abbreviation of preoperative fasting for 2 h, using carbohydrate and protein enriched solutions, is safe, reduces insulin resistance, and does not increase the risk of bronchoaspiration.

Keywords : Preoperative fasting; Carbohydrate and protein solution; Organic inflammatory response.

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