Abstract

SANTIAGO, Ana et al. Effects of weight loss after bariatric surgery on pulmonary function tests and obstructive sleep apnea in morbidly obese women. Nutr. Hosp. [online]. 2015, vol.32, n.3, pp.1050-1055. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.3.9487.

Introduction: obesity impacts on respiratory function and also it acts as a risk factor for obstructive sleep apnea (OSA). Aims: to study the effects of bariatric surgery on pulmonary function tests and on OSA in morbidly obese women over 4 years. Methods: fifteen morbidly obese women (mean body mass index [BMI] 50.52 ± 12.71 kg.m^-2, mean age 40.13 ± 10.06 years) underwent pulmonary function tests (PFT) in two opportunities (before and after weight loss surgery). PFT included spirometry, body plethysmography and measure of maximal inspiratory mouth pressure (PI_max) and of tension-time index for inspiratory muscles. Also, in both opportunities, resting arterial blood gas tensions were evaluated and a full night sleep register was performed. Results: BMI significantly decreased after bariatric surgery (-44.07 kg.m^-2 [CI 95% -38.32 - -49.81]). Also, there was a significantly increase in forced expiratory volume in 1 second (FEV₁) (p<0.01), forced vital capacity (FVC) (p<0.01), expiratory reserve volume (ERV) (p = 0.040), functional residual capacity (FRC) (p = 0.009) and a decline in airways resistance (Raw) (p = 0.018). Concerning sleep registers, apnea hypopnea index (p = 0.001) and desaturation index (p = 0.001) were also reduced after weight loss. Improve in ERV had a significant correlation with weight loss (r = 0.774, p = 0.024). Conclussions: pulmonary function tests and apnea hypopnea index improve after bariatric surgery in morbidly obese women. Improvement of ERV is well correlated with weight loss.

Keywords : Obesity; Pulmonary function test; Sleep apnea; Bariatric surgery.

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