Abstract

MIRAGLIA, Fernanda et al. Behavior of adipokines after a year follow-up in the Obesity Outpatient Clinic for Children and Adolescents. Nutr. Hosp. [online]. 2015, vol.32, n.4, pp.1554-1559. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.4.9464.

Objective: demonstrate adipokines progression, along 12 months, in obese children and adolescents who attend the Obesity Outpatient Clinic for Children and Adolescents of the HCPA. Methods: children and adolescents in medical treatment for obesity were followed for 12 months, assessing anthropometry, blood pressure, waist circumference, lipid profile, fasting blood sugar and insulin, inter leukine- 6, tumor necrosis factor alpha, and adiponectin in two points in time: at inclusion and after 12 months follow-up in the Obesity Outpatient Clinic for Children and Adolescents. Results: 27 children and adolescents were assessed with median age of 10.3 years. The mean BMI z-scores lowered during this period (p < 0.01), HDL-c increased in the period (p = 0.025). The medians of adipokines did not vary during the period: IL-6 (p = 0.470), TNF-α (p = 0.753) and adiponectin (p = 0.943). There was no correlation of IL-6 and TNF-α with central and global obesity along the 12-months follow-up. Adiponectin increased in 45% of the sample, the increase being more pronounced in females. Conclusion: children and adolescents in medical treatment for obesity, after one-year follow-up, did not improve their adiponectin profile.

Keywords : Children; Obesity; Adolescents; Adiponectin; Inflammation.

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