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Nutrición Hospitalaria
On-line version ISSN 1699-5198Print version ISSN 0212-1611
Abstract
CURVELLO-SILVA, Karine; RAMOS, Lilian; SOUSA, Cláudia and DALTRO, Carla. Phase angle and metabolic parameters in severely obese patients. Nutr. Hosp. [online]. 2020, vol.37, n.6, pp.1130-1134. Epub Feb 08, 2021. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.02928.
Introduction:
obese patients present an inflammatory and metabolic profile that leads to oxidative stress and cellular damage. Phase angle is an indicator of cellular integrity and has been proposed as a prognostic parameter for changes in the metabolic profile.
Objective:
to investigate the possible association between phase angle and metabolic parameters in obese patients.
Material and method:
this was a cross-sectional study of adult obese patients who attended a specialized clinic between 2014 and 2016. All patients were ≥ 18 years of age, with a body mass index ≥ 35 kg/m2. All data were obtained from medical records and made part of the clinical protocol. Patients were divided into two groups using a cutoff point for phase angle, and the groups were compared using the Kruskal-Wallis or Chi-squared test for quantitative and categorical variables, respectively. Correlations were identified by Spearman’s and Pearson’s correlation analyses. All between-group differences were considered statistically significant at p ≤ 0.05.
Results:
a low phase angle was present in 30.5 % of the 141 patients enrolled in the study. We found an association between low phase angle and presence of hyperuricemia (p = 0.018) when adjusted for waist circumference, dysglycemia, arterial hypertension, and hyperuricemia. There was no correlation between phase angle and the components of body composition.
Conclusions:
there is an association of phase angle with uric acid levels, but not with other metabolic parameters.
Keywords : Phase angle; Metabolic profile; Obesity; Bioimpedance; Cardiovascular risk; Uric acid.