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Nutrición Hospitalaria
On-line version ISSN 1699-5198Print version ISSN 0212-1611
Abstract
PALACIOS, Cristina et al. Associations between vitamin D levels and glucose metabolism markers among pregnant women and their infants in Puerto Rico. Nutr. Hosp. [online]. 2021, vol.38, n.6, pp.1224-1231. Epub Feb 07, 2022. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.03600.
Objectives:
low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism.
Methods:
maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/obesity (n = 31) and their infants at birth and 4 months.
Results:
insulin and HOMA-IR levels were higher among women with vitamin D below adequate levels compared to those with adequate levels in pregnancy (p < 0.05). Late in pregnancy, as vitamin D increased by one unit (ng/mL), insulin decreased by 0.44 units and HOMA-IR by 0.09 units. Maternal vitamin D late in pregnancy was correlated with infant vitamin D levels at birth (r = 0.89; p < 0.01) and 4 months (r = 0.9; p = 0.04), and with glucose (r = 0.79; p = 0.03) and insulin (r = 0.83; p = 0.04) at 4 months.
Conclusion:
maternal vitamin D status was associated with maternal and infant glucose metabolism in this sample.
Keywords : Vitamin D; Pregnancy; Infant; Glucose; Insulin.
