Abstract

LOPEZ-SAEZ, J. B.; QUINTELA SENRA, D.  and  SENRA VARELA, A.. Possible prognostic value of arterial hypertension in postmenopausal women with breast cancer in complete clinical remission: Pilot study. An. Med. Interna (Madrid) [online]. 2001, vol.18, n.3, pp.28-31. ISSN 0212-7199.

Background: The objective of this work was to determine the blood pressure of postmenopausal women with breast cancer in complete clinical remission of long duration. Material and methods: It in a pilot study of case and controls, in which we meassure the Blood Pressure (BP) of 83 postmenopausal women, with breast cancer histologically confirmed, in complete clinical remission of long duration, recruited by consecutive sampling, to compare it with that of 70 normal postmenopausal women of the same age used as controls. They ara calculated the body mass index (BMI), the corporal surface, the confidence intervals (CI) of the means, the correlation between the BMI and the BP in both groups (breast cancer patients and normal control) and between the free disease interval and the systolic and diastolic blood pressures.  Results: The mean of the systolic BP in 93 breast cancer patients in complete clinical remission was 163 mm Hg (95% CI 155-171) and in 70 normal controls was 134 mm Hg (95% CI 129-139). The difference between both groups in statistically significant (p<0.001). The mean of the diastolic BP in the breast cancer patient in complete remission it was 98 mm Hg (94-104) and in the normal controls was 78 mm Hg (74-82). The difference between both groups was statistically significant (p<0.001). Conclusions: This arterial hypertension, independent of the BMI and from the duration of the free disease interval, is associated with a long duration of the complete remission in postmenopausal breast cancer patients and consequently with a good prognostic of this disease.

Keywords : Breast cancer; Arterial hypertension; Angiotensin converting enzyme.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )