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Anales de Medicina Interna
Print version ISSN 0212-7199
Abstract
GARCIA TELLO, A.; VILLEGAS MARTINEZ, A. and GONZALEZ FERNANDEZ, A. F.. Haematological abnormalities in patients with systemic lupus erythematosus . An. Med. Interna (Madrid) [online]. 2002, vol.19, n.10, pp.53-57. ISSN 0212-7199.
Haematological abnormalities are frequently encountered in patients with systemic lupus erythematosus (SLE). Anaemia is the most common hematological abnormality in SLE, it is multifactorial. The most common form of anaemia is that of chronic disease, and it is relate with inflammatory cytokines. Other tips of anaemia are: iron deficiency anaemia, autoimmune haemolytic anaemia, pure red cell aplasia. Leucopenia is related to neutropenia and/or lymphopenia. Thrombocytopenia is common, autoimmune and associated with a decreased survival. The presence of antiphospholipid antibodies increase risk of thrombosis in patients with SLE.
Keywords : Systemic lupus erythematosus; Anaemia; Leucopenia; Thrombocytopenia; Antiphospholipid antibodies.