Abstract

SUAREZ ORTEGA, S. et al. Invasive infection due to Aspergillus Terreus treated successfully with liposomal anphotericin B. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.1, pp.20-22. ISSN 0212-7199.

A woman of 75 years old was admitted at our hospital for evaluation of worsening and weakness in inferior limbs. Several vertebral fractures by crushing, one doubtful discitis, an infitrate with cavitation in the right superior lobe and one infiltrate in the left superior lobe were detected. In the biopsy of the consolidation a filamentous fungus was watched and in the bronchial washing specimen culture grew Aspergillus terreus. The infiltrates disappeared with liposomal Anphotericin B remaining with oral Itraconazol durin three months more. The clinical and analytical data demonstrate the existence of a Overlap syndrome associate to antiphospholipid-antibody syndrome. We comment the peculiarity of the infection by Aspergillus terreus in patients who have not been in critical care and the good response at treatment with liposomal Anphotericin B. It contrasts with the high mortality referred in a recent review. Other aspects to comment are the coexistence with a collagen vacular and an antiphospholipid-antibody syndrome with the higher titles of IgM ACA that we have found in literature.

Keywords : Invasive aspergillosis; Aspergillus terreus; Corticoid; Collagen disease; Liposomal Anphotericin B.

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