Abstract

MARTIN MUNOZ, M. C. et al. Risk of infections and glycemic control in type 2 diabetes mellitus. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.3, pp.22-26. ISSN 0212-7199.

Background and objective: Although association between Diabetes Mellitus (DM) type 2 and prevalence of infections is a frequently considered issue in current literature there is few evidence of it. The objective of this study has been to analyse the infection risk in DM type 2 patients according to their glycemic control level (Hb Aic%). Patients and method: In this cohort-study of740 patients, we evaluated the incidence rates of infectious episodes inDM2-type diabetic patients during a period of 5 years, from May, 1997 to May, 2002. Results: The average period of follow-up was 4.26 years. We found no significant correlation (p=0.33) between higher levels of HbAic% and presentation of infections. Data clearly show a direct correlation betweenrisk of infection and number of associated chronic diseases (p=0.035), age (p=0.007) and diabetes duration (0.012). We also found an unexplained association between more aggressive treatment and higher glycemic levels (Hb Aic%) (p=0.0001) and also higher infection risk (0.038). Conclusions: Although there is no association between risk of infection and glycemic control (Hb Aic%) among analysed patients, this study shows a clear correlation between risk of infection and number of complications or number of associated chronic diseases.

Keywords : Diabetes Mellitus type 2; Infection; Risk; Cohort-study; Prevalence.

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