Abstract

RODRIGUEZ SALAZAR, M. J. et al. HIV-associated primary body-cavity-based lymphoma: clinico-biologic features in three patients diagnosed at the same institution. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.4, pp.27-30. ISSN 0212-7199.

Primary effusion lymphoma (PEL) is a recently individualized form of non-Hodgkin lymphoma (WHO classification) that mainly develops in HIV infected males, more frequently in homosexuals and advanced stages of the disease (total CD4+ lymphocyte count below 100-200/µL). Occasionally, it appears in others immunodepressive states (such as solid organs postransplant period) and even, although very rarelly, in immunocompetents patients. From a pathogenetic point of view, PEL has been related to Kaposi's sarcoma-associated herpes virus (also named human herpesvirus 8) and to the clinical antecedent of Kaposi's sarcoma. Relative unfrequency of this disease, the absence of wide casuistics allowing a better characterization, and its unfavorable outcome, support the need of a deeper knowledge. We present here the clinical-biological findings of three patients that were diagnosed of pleural PEL in our institution in the last two years.

Keywords : Human immunodeficiency virus, HIV; Primary effusion lymphoma.

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