Abstract

LADO LADO, F. L. et al. Statin-induced rhabdomyolysis and renal failure: also for fluvastatine. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.5, pp.35-37. ISSN 0212-7199.

Hydroximetilglutaril-coenzima A reductase inhibitors (statins) have de potential to cause rhabdomyolysis. However, fluvastatin is rarely associated with rhabdomyolysis when compared to other statins. Differences in biochemical and pharmacokinetic properties between fluvastatin and the other statins have been invocated in order to explain the apparent comparative safety of fluvastatin. We present a case of rhabdomyolysis with acute renal failure in a patient receiving fluvastatin and, following the Karch-Lasagne algorithm, we present evidence that this case was an adverse reactions to fluvastatin.

Keywords : Fluvastatin; Statins; Rhabdomyolysis; Renal failure.

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