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Anales de Medicina Interna

Print version ISSN 0212-7199

Abstract

MONTEJO, M. et al. Kikuchi-Fujimoto disease: review of four cases. An. Med. Interna (Madrid) [online]. 2006, vol.23, n.4, pp.173-175. ISSN 0212-7199.

Kikuchi Fujimoto disease is an uncommon form of lymphadenitis, firstly described in Japan. Etiology is unknown. It affects mainly young women. It commonly manifests as a painful cervical lymphadenitis usually associated with fever and leukopenia. Clinical course users to be benign, leading spontaneously to a complet recovery. Histological findings include necrotizing changes with cariorrhesis, partial loss of ganglionar architecture and foci of histiocytic infiltrates in the cortical and/or paracortical zones of the lymph nodes. A common findings is the absence of neutrophil granulocytes in the inflammatory infiltrates, in contrast to other necrotizing lymphadenitis. We report four cases of Kikuchi Fujimoto disease, recently identified in our hospital.

Keywords : Kikuchi-Fujimoto disease; Lymphadenitis.

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