Abstract

DOMINGUEZ ORTEGA, L.; MEDINA ORTIZ, O.  and  CABRERA GARCIA-ARMENTER, S.. Litium intoxication. An. Med. Interna (Madrid) [online]. 2006, vol.23, n.9, pp.441-445. ISSN 0212-7199.

Litium intoxication has a low prevalence, the 75% of patients with treatment with litium could have toxic levels of litium during the treatment. Asyntomatic patients have been observed with doses under 2.5 mmol/L. Systems with high prevalence of symptoms are the nervious system, gastrointestinal tube and cardiovascular. Symptoms could appear from two hours to four hours after ingestion. Early hours after Litium ingestion, levels of litium are not related with severity. However, monitoring seric levels is necessary to lead therapeutic approach and to give a prognosis. Induce urine with isotonic solution, is used during therapeutic approach. Other therapeutic option is dialysis. In summary, intoxication with litium could be a severe situation. It is necessary to describe therapeutic protocols in this entity.

Keywords : Litium; Intoxication; Farmacologic interaction; Diuretic; Renal function.

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