Abstract

HERNANDEZ MARIN, B. et al. Adrenal faillure caused by primary adrenal non-hodgking lymphoma: a case report and review of the literature. An. Med. Interna (Madrid) [online]. 2008, vol.25, n.3, pp.131-133. ISSN 0212-7199.

We report a case of 78-year old man who presented with symptoms of adrenal insufficiency. The computed tomography (CT) scan showed the presence of bilateral adrenal masses. A CT-scan guided needle biopsy revealed diffuse large- B cell lymphoma. The absence of pathological findings in clinical, bone marrow and CT scan examinations supported the diagnosis of primary non- Hodgkin Lymphoma of the adrenal glands. The patient was treated with four cycles of R-CHOP chemotherapy with Rituximab, liposomal Doxorubicin, Cyclophosphamide, Vincristine and Prednisolone. At the end of fourth cycle there was radiological improvement but the chemotherapy was stopped because of IV grade toxicity. He completed treatment with radiotherapy of right adrenal mass. Few days after finishing radiation therapy the pacient died due to a disseminated infection. No progressive disease was founded.

Keywords : Adrenal lymphoma; Adrenal faillure; Addison disease.

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