Abstract

GOMEZ HERNANDEZ, C.; DOMINGUEZ MARTIN, A.; GARCIA KASS, A.I.  and  GARCIA NUNEZ, J.A.. Adjunctive application of the photodynamic therapy and the Er:YAG laser radiation to non-surgical treatment of chronic periodontitis: comparative study of their clinical, anti-inflammatory and antimicrobial effects. Av Odontoestomatol [online]. 2011, vol.27, n.3, pp.147-160. ISSN 2340-3152.

Aim: To compare clinical, microbiological and anti-inflammatory effects of the photodynamic therapy (PDT) and the Er:YAG laser phototherapy adjunctively applied to scaling and root planning (SRP). Material and Methods: Forty-five patients with chronic periodontitis were randomly assigned into 3 groups of 15 patients to receive: SRP, SRP followed by PDT (SRP+PDT) or SRP followed by Er:YAG laser phototherapy (SRP+ERL). Clinical parameters including full mouth plaque score (FMPS), full mouth bleeding score (FMBS) and probing pocket depth (PPD) were recorded and samples of gingival crevicular fluid (GCF) and subgingival plaque were taken at baseline, 4 and 8 weeks postoperatively. The GCF samples were analyzed for interleukin-1beta (IL-1β), tumour necrosis factor alpha (TNF-α ) and total antioxidative status (TAS). Subgingival plaque was analyzed by culture for 10 bacteria. Results and Discussion: No statistically significant differences were detected between the three kinds of treatment concerning the evolution of the clinical parameters FMPS and PPD, the increase of TAS in GCF and the subgingival plaque reduction, but the SRP+ERL treatment slightly slowed down the bacterial recolonization process. Concerning the clinical parameter FMBS, a slight decrease was observed 8 weeks post-therapy after SRP+PDT treatment. Statistically significant differences between groups were observed in the evolution of the levels of the cytokines evaluated: after SRP the levels of IL-1β and TNT-α increased, significatively in the case of TNT-α at 8 weeks post-therapy. The procedure SRP+PDT showed a trend to slow down this increase, and after the application of SRP+ERL these levels decreased, more severely in the case of IL-1β, during the whole post-therapy period.

Keywords : Photodynamic therapy; Er:YAG; SRP; chronic periodontitis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )