Abstract

CANO PARRA, J  and  DIAZ-LLOPIS, M. Drug induced uveitis. Arch Soc Esp Oftalmol [online]. 2005, vol.80, n.3, pp.137-149. ISSN 0365-6691.

Purpose:To review the world literature about drug induced uveitis. Methods: We used the OMS and Naranjo criteria of causality of adverse drug reactions to classify the causes of drug induced uveitis. These have been classified into certain, probable and possible causes. We described the clinical features associated with each drug. Results: Certain causes of uveitis are byphosphonates, topiramato and metipranolol eyedrops. Probable causes are rifabutin, sulfonamides, cidofovir, immunorecovery in patients following HAART therapy, topical corticosteroids, latanoprost, and intravitreous triamcinolone acetate. Possible causes of uveitis include bimatoprost, travoprost, brimonidine, other eyedrops and intraocular drugs, tubulointerstitial nephritis and uveitis (TINU) produced by nonsteroidal drugs, iopamidol, diethylcarbamazepine, interleukins 3 and 6, oral contraceptives, quinidine, vaccines and cobalt, ibuprofen and moxifloxacin. Conclusion: Drug induced uveitis is an entity of low incidence, anterior iridocyclitis is the commonest clinical picture, visual acuity is moderately diminished, and if use of the drug is ceased uveitis does not recur.

Keywords : Uveitis; drugs.