Abstract

LARIA-OCHAITA, C  and  ALIO-Y-SANZ, JL. Corneal intra-epithelial neoplasia (CIN): Treatment by combined excision and antimetabolite therapy. Arch Soc Esp Oftalmol [online]. 2005, vol.80, n.11, pp.671-674. ISSN 0365-6691.

Case Report: We present two clinical cases of corneal intra-epithelial neoplasia defined histopathologically. Discussion: We sought to establish the importance of treatment with Mitomycin-C in two cases of corneal intra-epithelial neoplasia. The differential diagnosis was established based on the evolutionary character of the process, as well as specific histopathological aspects of these entities. In both cases, treatment with Mitomycin-C before, during and after surgery contributed to the decrease in the size of the lesion and to their cure without relapse.

Keywords : Corneal intra-epithelial neoplasia; corneal dysplasia; epithelial dysplasia; conjunctiva; mitomycin-C.