Abstract

ASENSIO-SANCHEZ, V.M. et al. Severe ocular side effects with Topamax. Arch Soc Esp Oftalmol [online]. 2006, vol.81, n.6, pp.345-348. ISSN 0365-6691.

Case reports: We describe 2 patients who developed ocular side effects during treatment with topiramate. One was a 16-year-old woman with generalized seizures who developed a homonymous hemianopia after using topiramate 125 mg per day for 12 weeks, and the other was a 24-year-old epileptic female who developed a bilateral maculopathy after using topiramate 150 mg per day for 8 weeks. Discussion: We identified two severe ocular adverse reactions from topiramate. Both reactions necessitated discontinuing the treatment, but the topiramate-associated maculopathy was irreversible.

Keywords : Topiramate; homonymous hemianopia; maculopathy.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )