Abstract

ALVAREZ-RIVERA, L.G. et al. Coat's disease treated with bevacizumab (Avastin^®). Arch Soc Esp Oftalmol [online]. 2008, vol.83, n.5, pp.329-331. ISSN 0365-6691.

Case Report: We report a case of Coats’ disease in a 10-year-old-girl who presented with a profound visual deficit, exudative retinal detachment, vascular telangiectasias and subretinal lipid, who underwent treatment with an intravitreal injection of bevacizumab (AVASTIN™). Serial examinations documented an involutional response with a reduction of the subretinal fluid, exudates and macular thickness. Discussion: The aetiology of Coats’ disease remains uncertain, as does its optimal management. Although resolution of a case depends partially on age, and can even occur spontaneously on rare occasions, intravitreal injections of bevacizumab should be considered when planning treatment.

Keywords : Vascular endothelial growth factor; Coats’ disease; monoclonal antibodies; angiogenesis inhibitors; telangiectatic retinal vessels.

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