Abstract

FERNANDEZ JIMENEZ-ORTIZ, H.; PERUCHO MARTINEZ, S.; TOLEDANO FERNANDEZ, N.  and  MARTIN GIRAL, E.. Intracameral bevacizumab (Avastin^®) in the management of neovascular glaucoma surgery. Arch Soc Esp Oftalmol [online]. 2012, vol.87, n.12, pp.396-400. ISSN 0365-6691.  https://dx.doi.org/10.1016/j.oftal.2011.09.025.

Purpose: To describe a case series of neovascular glaucoma treated with intracameral bevacizumab prior to filtering surgery. Design: Descriptive, retrospective case series. Methods: Five eyes of 5 patients with neovascular glaucoma due to any cause candidates to filtering surgery who had previously received an injection of intracameral bevacizumab (1.25mg/0.05ml) as treatment for neovascularization of anterior chamber. Results observed one week and 4 weeks postsurgery are reported. Results: Bevacizumab produced regression of the angle neovascularization and the intraocular pressure. Only one case of postoperative bleeding was detected. Conclusions: Intracameral bevacizumab prior to filtering surgery of neovascular glaucoma diminished the neovascularization and intraocular pressure after 4 weeks of its administration and was effective in preventing intraoperative and postoperative bleeding. It also constitutes a promising way of investigation to prevent surgical complications.

Keywords : Bevacizumab; Glaucoma neovascular; Filtering surgery; Angiogenesis inhibitors; Injections intraocular.

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