Abstract

ALVES, R.; CASTRO ESTEVES, T.  and  TRELLES, M.A.. Intrinsec and extrinsec factors related to cutaneous aging. Cir. plást. iberolatinoam. [online]. 2013, vol.39, n.1, pp.89-102. ISSN 1989-2055.  https://dx.doi.org/10.4321/S0376-78922013000100013.

As human life expectancy increases, more interesting studies arise in order to better understand the complex process that aging involves. The perception of age is largely dependent on the appearance of exposed skin. Aging is a complex and multifactorial process resulting in the accumulation of several functional and aesthetic changes in an organism over time. The skin is also affected by these changes through intrinsic and extrinsic factors. Intrinsic aging or biological aging is an inevitable process, genetically determined that progresses slowly over the years as we age. It can be accelerated by environmental factors. The main factors responsible for extrinsic aging are primally cumulative sun-exposure and tobacco smoke. Aging is not only about the cellular processes involved, but it is also a response to the adaptation of environmental stressors. The focus of this review is to better understand the mechanisms responsible for the intrinsic aging and to identify the principal extrinsic factors and how they can accelerate the cellular processes.

Keywords : Aging; Intrinsic aging; Extrinsic aging; Photoaging.

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