Abstract

SERNA-CUELLAR, E.  and  SANTAMARIA-SOLIS, L.. Protocol of extraction and processing of adult stem cells from abdominal adipose tissue: coordenates of the plastic surgeon in translational researching. Cir. plást. iberolatinoam. [online]. 2013, vol.39, suppl.1, pp.s44-s50. ISSN 1989-2055.  https://dx.doi.org/10.4321/S0376-78922013000500012.

Adult stem cells-based therapy represents the most innovative treatment to regenerate the pathologic tissues (absent or lacking), to "replace like with like" as an aesthetic filler for a variety of cosmetic and reconstructive indications, and is one of the trending translational research lines all over the world; avoiding the host immune response and implant rejection problems of the human allotransplants, the inherent complications due to the implantation of alloplastic materials, the functional and aesthetic secuelae of donor sites in high morbidity autotrasplants, and the bioethical problems with the use of embrionary stem cells. Plastic surgeon has a relevant role such in the extraction of the cellular graft from the abdomen by means of a tumescent manual liposuction, as in the quick clinical application to different defects, deformities and losses of substance. The protocol of extraction and processing of adipose derived stem cells (ADSC) approved by the Clinical Researching Ethical Committee is presented as a feasible, safe and reproducible guide for the design of new controlled clinical studies about the efficacy of the stem cell autotrasplants for the treatment of many pathologies inside the universe of plastic surgery in which scarring process is compromised.

Keywords : Adipose tissue; Lipofilling; Stem cells.

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