Abstract

MERCEDES-ACOSTA, Severo et al. Evolution of the postabdominoplasty surgical scar after injection of platelet-rich plasma. Cir. plást. iberolatinoam. [online]. 2016, vol.42, n.4, pp.331-338. ISSN 1989-2055.

Background and Objectives. Scarring is the natural healing process of the skin recovery after injury. Abdominoplasty is one of the most requested surgical interventions in plastic surgery; one of its predominant concerns is the resulting scar. The platelet-rich plasma (PRP) contains growth factors involved in tissue regeneration. Our goal is to determine the evolution of the post-abdominoplasty surgical scar after injection of PRP. Patients and Methods. We conduct an observational, prospective cohort, double- blind, in which 26 female patients were included, aged between 25 and 50 years, with no skin or systemic disorders, to whom were performed conventional abdominoplasty and infiltration of PRP on the scar on the randomly chosen side, immediately after surgery. Macroscopic and histological characteristics where evaluated on both sides of the scar. All tummy tucks were performed by the same surgical team and evaluations of macroscopic findings, were made by 4 different examiners, at 21 days and in the third month post-surgery. Results. Macroscopic characteristics at 21 days presented were: dehiscence 16 cases for 61.5% of controls cases, versus 2 cases for 7.7% of cases with PRP. The widening occurred in 13 cases for 50% in controls cases versus 3 cases for 11.5% in cases with PRP. Similarly, the elevation was observed in 12 cases for 46.1% of control cases versus 4 cases for 15.4% of the PRP. At 3 months, these clinical characteristics investigated reported similar findings. Biopsies were processed and analyzed for 3 dermatopathologists on equal terms to the previous analysis. The predominant histological features at 21 days were: mild perivascular inflammation in 20 cases for 76.9% in cases with PRP and moderate swelling over foreign body reaction in 20 controls cases for 76.9%. Predominance of thin collagen fibers with abundant mucopolysaccharides in patients with PRP 18 cases for a 69.2% cases versus controls cases with thick collagen fibers and mucopolysaccharides decreased in 19 cases for 73.1%, elastic fibers predominantly in the PRP cases with 16 cases for 61.5%. At 3 months the most relevant features were greater amount of thick collagen fibers in cases with PRP for 14 cases and 53.9% fewer cases mucopolysaccharides 8 to 30.8%. Conclusions. In our study, the use of PRP in the immediate postoperative of abdominoplasty, offers a better cosmetic scar, with both macroscopic and histological appearance.

Keywords : Abdominoplasty; Scar; Platelet-rich plasma.

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