Abstract

GARCIA-BUENDIA, Ginés; CANOVAS-SANCHIS, Sergio; MORALES-CANO, María-Dolores  and  DIAZ-NAVARRO, María-José. Evaluation of the facial lipoatrophy treatment with polyacrylamide gel. Cir. plást. iberolatinoam. [online]. 2017, vol.43, n.2, pp.143-155. ISSN 1989-2055.

Background and Objective. Facial lipoatrophy is a frequent complication of patients with HIV/AIDS associated with antiretroviral therapy. It consists of an abnormal facial fat loss, which poses a serious personal, occupational and social problem for these patients resulting in a lack of adherence to the treatment. Treatment by infiltration of filling materials is required to correct the established facial lipoatrophy. The objective of this study is to assess the effectiveness and safety of the facial lipoatrophy treatment filled with polyacrylamide gel. Methods: A one-year prospective follow-up study is carried out in 15 patients with facial lipoatrophy grades II-III. Side effects are measured. The permanence of the facial filler is analyzed by TAC and the evolution in facial lipoatrophy grades, in the degree of involvement of the patient and its satisfaction after surgery. Results: A 100% of the sample did not portray any side effects in the year of monitoring. A significant decrease in the thickness of the facial filler or in the satisfaction of the patients could not be found a month and a year after the treatment. There is a statistically significant decline in the degree of involvement of the patient and the extent of facial lipoatrophy after treatment with p < 0.0001. Conclusions: Polyacrylamide gel is a safe and effective filling material for the facial lipoatrophy treatment of in HIV+ patients in stable clinical situation.

Keywords : HIV; AIDS; Antiretroviral therapy; Lipodystrophy; Dermal fillers; Polyacrylamide.

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