Abstract

MARTINEZ-MENDEZ, José-Ramón et al. Consensus guideline about the use of the enzimatic debridement in burn injuries with NexoBrid^®. Cir. plást. iberolatinoam. [online]. 2017, vol.43, n.2, pp.193-202. ISSN 1989-2055.

Background and Objective: Early debridement is considered the keystone of the burn injuries treatment. It is well known that the eschar removal during the first 72 hours is the best option to reduce the hospital stay and the infectious events. However this treatment compromise the preservation of viable dermis, needed to reach the best functional and aesthetic outcome, therefore grafting the wound bed is mandatory. There is increasing evidence that enzymatic debridement with NexoBrid^® is showing a reduction in the grafting rate, the blood loss and the number of surgical excisions. The objective of this consensus meeting is providing guidelines based in Spanish experts experiences. Methods: A panel of 7 experts from the main Spanish Burn Units were design, with more than 350 patients treated by them, where the different statements were discussed, trying to get a consensus guideline of the indication, use and management of NexoBrid^®. Results: A high level agreement was stated. All the aspects of NexoBrid^® treatment were discussed showing an agreement of 70%, as well as the indications and limitations of its use. All new evidence published so far this paper was included. Different treatment options used by the Spanish Burn Centers were discussed, showing a global recommendation in their use. Conclusions: A consensus document was created as a preliminary guideline for the NexoBrid^® use until further guidelines are available. There is no other consensus guideline published so far this document.

Keywords : Burns; Burns treatment; Burns debridement; Enzymatic debridement.

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