Abstract

VERA GARCIA, Pablo J; MORENO VILLABA, Ramón A; FERNANDEZ PASCUAL, Clemente J  and  REGO HERMIDA, Patricia. First case in region of Murcia (Spain) of breast implant-associated anaplastic large cell lymphoma. Cir. plást. iberolatinoam. [online]. 2019, vol.45, n.3, pp.235-242.  Epub Dec 16, 2019. ISSN 1989-2055.  https://dx.doi.org/10.4321/s0376-78922019000300004.

Breast implant-associated large cell anaplastic lymphoma is an extremely rare entity of which, until January 2019, 656 cases have been diagnosed in 34 countries with 17 reported deaths. It´s etiology is postulated as the result of a foreign body reaction to the implant and the resultant chronic and persistent inflammation.

We present the first case of this pathology diagnosed and treated in the Region of Murcia, Spain. A patient with chronic relapsing seroma that appears 5 years after breast implant placement after diagnosis and treatment for breast cancer. The definitive diagnosis was obtained in the pathological and immunohistochemical study of the periprosthetic capsule after implant removal surgery and bilateral complete capsulectomy. Postoperative chemotherapy was administered on the recommendation of the hospital Tumor Committee.

Keywords : Breast implant-associated large cell anaplastic lymphoma; Breast implants; Breast prosthesis; Delayed seroma.

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