Abstract

BERMEJO AYCART, J. I. et al. Sarcomas de útero después de tratamiento con tamoxifeno por cáncer de mama. Oncología (Barc.) [online]. 2005, vol.28, n.7, pp.38-42. ISSN 0378-4835.

PURPOSE: Description of two cases of sarcoma in women who received tamoxifen after the surgical treatment of breast cancer. MATERIAL AND METHODS: We report two cases of 74 and 53 years old women that received tamoxifen 20 mg daily after the surgical treatment of breast cancer. Four and two years after initiation of tamoxifen treatment, they developed an heterologous malignant mixed Müllerian tumor (stage III) and an endometrial stromal sarcoma (stage I), respectively. DISCUSSION: Carcinosarcomas and other uterine sarcomas are rare, accounting for fewer than 4% of uterine tumors. Most studies reported on a higher rate of these sarcomas among postmenopausal women with breast cancer treated with tamoxifen when compared with non-treated patients, especially those exposed to a long term treatment.

Keywords : Uterine sarcoma; Tamoxifen; Breast cancer.

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