Abstract

GENTIL GONZALEZ, M. et al. Gliomatosis Cerebri: diagnosis and treatment with temozolomide. About a case. Oncología (Barc.) [online]. 2007, vol.30, n.3, pp.41-45. ISSN 0378-4835.

Gliomatosis cerebri (GC) is a rare difuse, infiltrative and non destructive primary brain tumor from glial origin The term GC implies the affection of two or more brain lobes with possible extension to brain stem, cerebellum, spinal cord and subarachnoid space. Clinical features are unspecific, so diagnosis comes from characteristic features in neuroimagin studies (fundamentally IRM) but histological confirmation is required for diagnosis. Radiotherapy treatment can improve or stabilize neurological function in some patients, its impact on survival has not been demonstrated. Encouraging alternative treatment, as chemotherapy treatment with temozolomide, has recently arisen. We present a case of GC in a 49 years old male treated with temozolomide as a single therapy.

Keywords : Gliomatosis cerebri; Temozolomide; Primary brain neoplasm.

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