Abstract

ADAN MERINO, L. et al. Chronic hepatitis C treatment in a cystic fibrosis patient in the pulmonary pre-transplant stage. Rev. esp. enferm. dig. [online]. 2010, vol.102, n.10, pp.587-590. ISSN 1130-0108.

The standard treatment of chronic hepatitis C, pegylated interferon and ribavirin (pegI/R), has many limitations in both effectiveness and secondary effects, which makes it unsuitable or even contraindicated for some patients. In hepatitis C virus-infected cystic fibrosis patients this treatment could increase respiratory infections with subsequent pulmonary function deterioration. On the contrary, hepatitis C virus (HCV) infection may make lung transplant (LT) unfeasible. We present the case of a cystic fibrosis-young man diagnosed with HCV infection during LT assessment who was treated with pegI/R. In spite of the lung function worsening and respiratory infections, he managed to complete treatment and even sustained virological response (SVR). At present he is on LT waiting list.

Keywords : Hepatitis C; Cystic fibrosis; Lung transplant; Pegylated interferon; Ribavirin; Respiratory infections.

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