Abstract

SALAZAR FERNANDEZ, C.I. et al. Preliminary study of the sentinel node in oral cancer: in conjunction with 12 cases. Rev Esp Cirug Oral y Maxilofac [online]. 2004, vol.26, n.3, pp.155-163. ISSN 2173-9161.

Abstract: IManagement of the N0 neck in patients with head and neck squamous cell carcinoma remains controversial. Objective. To evaluate the feasibility and predictive ability of the sentinel node (SN) localization-biopsy technique for patients with squamous cell carcinoma of the oral cavity and clinically negative necks. Methodology. We realize a prospective study of 12 consecutive patients at present, with squamous cell carcinoma oral and clinically negative necks. These patients had not recived treatment against tumor and they were assited by Maxillofacial Surgery Service of HUVM from Seville. All patients received a cervical Tc99mlymphoscintigraphy to localize the sentinel node and a new dose before surgery. Intraoperatively, the sentinel node is localized and it is removed separately before tumor resection and elective functional neck dissection. The different anatomic specimens are sent for independent histological examination. Results. lympholocalization 91%, radiolocalization 100%, false negative 0%, sensitivity and NPV 100%, likely hood ratios > 10 and likely negative ratios < 0.1. Conclusions. The technique allows identification of SN-metastases and shows promise in guiding functional neck dissection (FIS-2002 subvention)

Keywords : Sentinel node; Oral squamous cell carcinoma; Cervical lymphoscintigraphy; Elective cervical dissection.

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