Abstract

GUZMAN CASTILLO, Galo Fernando et al. Epidermodysplasia verruciformis as a predisposal entity for squamous cell carcinoma. A familial case report. Rev Esp Cirug Oral y Maxilofac [online]. 2021, vol.43, n.2, pp.71-75.  Epub Sep 13, 2021. ISSN 2173-9161.  https://dx.doi.org/10.20986/recom.2021.1261/2021.

Epidermodysplasia verruciformis is a rare genodermatosis, in which there is an increased susceptibility for human papillomavirus (HPV) infection and the subsequent apparition of malignant tumours, being the squamous cell carcinoma the most frequent of those. We present this familiar case report of two male siblings who presented advanced squamous cell carcinoma in the facial area and lesions in arms and forearms, who were taken to major surgical resection, cervical lymph node resection and microvascular free flap reconstruction.

Keywords : Epidermodysplasia verruciformis; squamous cell carcinoma; human papilomavirus; genodermatosis.

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