Abstract

GARCIA-MOLINA, Francisco et al. Parotid metastasis of clear cell renal carcinoma with simultaneous presence of arterial pseudoaneurysm. Case report and review of literature. Rev Esp Cirug Oral y Maxilofac [online]. 2022, vol.44, n.3, pp.112-118.  Epub Feb 13, 2023. ISSN 2173-9161.  https://dx.doi.org/10.20986/recom.2022.1370/2022.

Parotid gland metastases are very rare. We present the case of a 73-year-old woman whose main oncological history to highlight is infiltrating ductal carcinoma of the breast treated with mastectomy and axillary lymphadenectomy and after that. metachronous bilateral clear cell renal cell carcinoma treated with radical nephrectomy. Since then, the woman has been on dialysis. It presents a 4 cm parotid tumor, which is radiologically classified as an intraparotid arterial pseudoaneurysm. After extirpation of the parotid gland, six years after the last nephrectomy, in the pathological study, together with dilated vessels, a neoplastic lesion compatible morphologically and immunohistochemically with metastasis of clear cell renal cell carcinoma is observed. A thorough review of the literature has been carried out, finding less than 60 reported cases of parotid metastasis from clear cell renal cell carcinoma. Analyzing them, we observed metastases in other places in 61 % of them, mainly lung, bone and adrenal glands, with a higher percentage of second metastases (70 %) when there was a synchrony between renal carcinoma and parotid metastasis.

In conclusion, we have presented an unusual case of late metastasis of clear cell renal carcinoma in the parotid, and the first -to our knowledge-, which is diagnosed as an incidental finding in the removal of an intraparotid aneurysm.

Keywords : Parotid gland; metastases; clear cell renal cell carcinoma; immunohistochemistry; pseudoaneurysm.

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