Abstract

GIMENO ORNA, J. A. et al. Self monitoring of blood glucose as a predictor of glycated hemoglobin. Medifam [online]. 2001, vol.11, n.6, pp.31-38. ISSN 1131-5768.

Introduction and objectives: self monitoring of blood glucose in patients with type 2 diabetes could reflect the quality of metabolic control. The objective was to evaluate in which moments of the day capillary blood glucose showed the best correlation with glycated hemoglobin (HbA1c) values and to establish capillary blood glucose cut-off in order to predict HbA1c values higher and lower than 7.5%.  Design: cross-over, descriptive study.  Material and methods: three capillary blood glucose profiles were practised at home to 42 patients with type 2 diabetes mellitus: one of them on the day before HbA1c determination and the other ones four and eight weeks before that HbA1c determination. Each profile included six checking points, before and two hours after breakfast, lunch and dinner.  Results: the best correlation between capillary blood glucose and HbA1c was obtained before breakfast (r=0,44; p=0.0047) and before dinner (r=0.44; p=0.0041). The ROC curve of blood glucose obtained before breakfast to predict HbA1c with 7.5% cut-off had an area under graph of 0.694. The optimal blood glucose value choosed was 145 mg/dl.The ROC curve of blood glucose obtained before dinner had an under graph area of 0.739; the blood glucose value choosed was 141 mg/dl.  Conclusions: blood glucoses that showed the best correlation with HbA1c values were the ones before breakfast and dinner. Due to poor correlation between HbA1c and capillary blood glucoses, selfmonitoring blood glucose should be considered orientative and not sustitutive of HbA1c determination.

Keywords : Self monitoring blood glucose; Glycated hemoglobin.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )