SciELO - Scientific Electronic Library Online

 
vol.19 issue5Multicultural informative triptych of post-surgery acute painUltrasound-assisted and interventionism study of shoulder joint author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista de la Sociedad Española del Dolor

Print version ISSN 1134-8046

Abstract

MONERRIS TABASCO, M. M. et al. Efficacy and safety of single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) for gonarthrosis pain treatment. Rev. Soc. Esp. Dolor [online]. 2012, vol.19, n.5, pp.259-263. ISSN 1134-8046.

Objective: to evaluate the effectiveness and safety of single-dose injection of stabilized hyaluronic acid of non-animal origin (NASHA) for the treatment of pain related to knee osteoarthritis. Material and methods: we included a total of 37 patients with previously diagnosed gonarthritis by the Orthopedist/Rheumatologist in which conservative treatment has failed and/or who are not candidates for surgery. They carried out a single-dose injection of non-animal stabilized hyaluronic acid (Durolane®). We collected demographic data, adverse effects and pain intensity (assessed by verbal numeric scale) and scores on the questionnaires Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Barthel -baseline, at 2 weeks, at 3 months and 6 months of infiltration-. It has been considered effective a decrease ≥ 30% for more than 3 months at baseline scores. Results: patients are predominantly female (83.8%) with a mean age of 72.8 years (standard deviation = -S-8.4) and mean body mass index (BMI) 31.9 (S = 6.9). The left knee is infiltrated in 51.7%, 41.4% right and bilateral in 6.9% of patients. Adverse effects have occurred as well tolerated arthralgia 11.1% of patients. Based on the results, the infiltration with single dose of stabilized hyaluronic acid of non-animal origin for osteoarthritic source gonalgia caused a statistically significant reduction in pain intensity (numerical verbal scale and WOMAC) and functional capacity (WOMAC) at all measured intervals. There has been a ≥ 30% reduction in pain intensity in 54% (value that matches the reduction in WOMAC pain score) in 62.1% stiffness and functional capacity in 48.6% of patients. Conclusion: in our patients, intra-articular viscosupplementation single dose of stabilized hyaluronic acid of non-animal origin (NASHA, Durolane®) for the treatment of pain related to gonarthritis has been effective and safe and is a weapon for the management of pain and disability gonarthritis generated.

Keywords : Viscosupplementation; Gonarthrosis; Chronic pain; Non animal stabilized hyaluronic acid.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License