Abstract

TORNERO-TORNERO, JC  and  FERNANDEZ RODRIGUEZ, LE. Platelet rich plasma and intra-articular mesenchymal stem cells in osteoarthritis. Rev. Soc. Esp. Dolor [online]. 2021, vol.28, suppl.1, pp.80-84.  Epub Mar 08, 2021. ISSN 1134-8046.  https://dx.doi.org/10.20986/resed.2021.3858/2020.

Osteoarthritis is a degenerative disorder that progresses slowly and is becoming more and more common in our population. Until a few years ago, it has been treated with oral analgesics, intra-articular injections with corticosteroids, botulinum toxin and hyaluronic acid and even with surgical joint replacement in the most advanced cases.

Regenerative medicine is the great hope in the treatment of this pathology to improve the quality of life of patients and try to slow down its progression. There are two types of regenerative intra-articular injection therapies that we must differentiate, PRP (Platelet-rich plasma) and MSC (Mesenchymal stem cells) with promising results.

Although there is the potential benefit of biological therapies acting directly on the affected joint, rigorous and well-designed clinical trials are necessary to establish the safety and efficacy of these therapies.

Keywords : Osteoarthritis; intra-articular injection; platelet-rich plasma; stem cells.

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