Abstract

ABALO-DELGADO, R  and  DE SANTIAGO-MORAGA, J. Medical cannabis treatment in patients with visceral chronic pain. Rev. Soc. Esp. Dolor [online]. 2022, vol.29, suppl.1, pp.32-42.  Epub Nov 28, 2022. ISSN 1134-8046.  https://dx.doi.org/10.20986/resed.2022.4030/2022.

Chronic visceral pain is very common and disabling. Chronic secondary visceral pain must be distinguished from chronic primary visceral pain states that are considered diseases in their own right. Primary chronic visceral pain is a category of nociplastic-like pain, characterized by impaired nociception without clear evidence of actual or potential tissue damage. Management of primary chronic visceral pain is challenging, either due to lack of pharmacological efficacy or intolerance to side effects. In this context, treatment with cannabinoids can be a useful alternative in these patients.

In this review, after briefly explaining the pathophysiological mechanisms involved in chronic visceral pain and its relationship with the endocannabinoid system, we will show the current evidence on the use of cannabinoids in the treatment of chronic visceral pain.

Keywords : Medical cannabis; chronic pain; visceral pain; evidence.

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