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Anales del Sistema Sanitario de Navarra
Print version ISSN 1137-6627
Abstract
LOZA, E.. Treatment of postmenopausal osteoporosis. Anales Sis San Navarra [online]. 2003, vol.26, suppl.3, pp.91-98. ISSN 1137-6627.
Prevention and treatment of osteoporosis consists of non-drug and drug therapy. This review of the topic will provide an overview of the approach to therapy of osteoporosis in postmenopausal women. In the past, estrogen replacement was considered a primary therapy for the prevention of postmenopausal osteoporosis. However, data from the Women´s Health Initiative (WHI) revealed that estrogen-progestine therapy does not reduce the risk of coronary heart disease, and increases the risk of breast cancer, stroke, and venous thromboembolic events. As a result of these findings, other antiresorptive agents are now the drugs of choice for the prevention and treatment of osteoporosis in postmenopausal women.
Keywords : Postmenopausal osteoporosis; Treatment; Bisphosphonates; Raloxifene; Calcitonin.