SciELO - Scientific Electronic Library Online

 
vol.40 issue1Scales for predicting outcome after severe traumaOrigin of newborn screening programs and their beginnings in Spain author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Anales del Sistema Sanitario de Navarra

Print version ISSN 1137-6627

Abstract

GARCIA-LAMBERECHTS, E.J. et al. Factors predicting failure in empirical antibiotic treatment. Anales Sis San Navarra [online]. 2017, vol.40, n.1, pp.119-130. ISSN 1137-6627.  https://dx.doi.org/10.23938/assn.0011.

Infections are one of the main causes of morbidity and mortality in the population. The choice of empirical treatment is one of the most common decisions facing the physician. This first decision has consequences in the prognosis of the patient and the costs associated with the process. This review attempts to summarize the aspects that can lead to failure of antibiotic treatment by considering microbiological and pharmacological aspects, patient profile and infectious focus control. In addition, a series of recommendations are established to minimize this risk, from the point of view of diagnostic accuracy, adequate severity stratification of the patient, knowledge of the pharmacokinetic and pharmacodynamic aspects of antibiotics and control of the infectious focus.

Keywords : Antibiotic; Adequacy; Inappropriate treatment; Infection; Emergency.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )