Abstract

VIERA-MOLINA, M.  and  GUERRA-MARTIN, M.D.. Analysis of the effectiveness of assisted reproduction techniques: a systematic review. Anales Sis San Navarra [online]. 2018, vol.41, n.1, pp.107-116. ISSN 1137-6627.  https://dx.doi.org/10.23938/assn.0254.

There are a high number of people affected by infertility who require assisted reproduction techniques. For this reason the aim of this review was to analyze the effectiveness of the interventions carried out using these techniques. A systematic peer review was performed on twelve databases. Inclusion criteria were: randomized clinical trials, published between 2011 and 2016, and with a score greater than two on the Jadad scale. The pharmacological interventions that proved effective were the administration of hormones, intrauterine human chorionic gonadotropin, gonadotrophin and dehydroepiandrosterone, and metformin. An effective surgical intervention, endometrial scratching, was identified. No effective non-pharmacological interventions were found. Assisted reproduction techniques show heterogeneity in both the interventions included and effectiveness criteria (pregnancy rate, live birth rate or implantation rate), which makes a unification of criteria necessary.

Keywords : Reproductive assisted techniques; Clinical trial; Treatment outcome; Effectiveness; Review.

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