Abstract

MARBAN CALZON, Mercedes; GONZALEZ JIMENO, Alicia; GARCIA BERMEJO, Alba  and  BELMONTE PINTRE, Zaira. Rare thyroid hormone profile. Thyroid hormone resistance syndrome. Rev Pediatr Aten Primaria [online]. 2019, vol.21, n.81, pp.e1-e5.  Epub Oct 14, 2019. ISSN 1139-7632.

It can only be ensured that thyroid function is normal when thyroid-stimulating hormone and free thyroid hormones thyroxine and triiodothyronine levels are normal. A hormonal pattern with elevated free thyroxine and triiodothyronine and unsuppressed thyroid-stimulating hormone is very rare, and its main cause is thyroid hormone resistance syndro¬me, a rare genetic entity that can associate symptoms of hypo and hyperthyroidism and whose diag¬nosis requires a high rate of suspicion. In children, the sole or main manifestation may be an attention deficit hyperactivity disorder. We present a family characterized by the initial diagnosis of twin sisters at 20 months of age.

Keywords : Free thyroid hormones; Thyroid hormone resistance.

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