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Medicina Oral, Patología Oral y Cirugía Bucal (Internet)

On-line version ISSN 1698-6946

Abstract

GARCIA DE MARCOS, José Antonio et al. Gingival neurofibroma in a neurofibromatosis type 1 patient: Case report. Med. oral patol. oral cir.bucal (Internet) [online]. 2007, vol.12, n.4, pp.287-291. ISSN 1698-6946.

Neurofibroma is a benign peripheral nerve sheath tumour. It is one of the most frequent tumours of neural origin and its presence is one of the clinical criteria for the diagnosis of type 1 neurofibromatosis (NF-I). Neurofibromatosis type 1 is an autosomal dominantly inherited disease due to an alteration in the long arm of chromosome 17. About 50% of NF-I patients have no family history of the disease. NF-I patients have skin lesions (café au lait spots and neurofibromas) as well as bone malformations and central nervous system tumours. Diagnosis is based on a series of clinical criteria. Gingival neurofibroma in NF-I is uncommon. Treatment of neurofibromas is surgical resection. The aim of this paper is to report a case of NF-I with gingival involvement and to review the literature.

Keywords : Type I neurofibromatosis; NF-I; neurofibroma; Von Recklinghausen’s disease; gum.

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