Abstract

BASCONES, A.  and  GONZALEZ MOLES, M.A.. Immunological mechanism of the periodontal and the periimplants diseases. Avances en Periodoncia [online]. 2003, vol.15, n.3, pp.121-138. ISSN 2340-3209.

A review is presented of immunological mechanisms and the destructive process of periodontitis. It begins with the basic concepts of natural and acquired immunity and continues with a study of antigen recognition, inflammation mediators, lines of defence of the organism and risk factors implicated in the disease. This is followed by an exploration of the apoptotic mechanism and an evaluation of the metalloproteinases that are released and are responsible for the periodontal destruction. Special attention is also paid to the pathogenesis of the periodontal pocket and bone reabsorption that are consequences of these mechanisms. Finally, we summarise all of these factors related to periodontitis and provide an assessment of the risk factors.

Keywords : Periodontitis; immunology; interleukins; apoptosis; risk factors.

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