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Revista de la OFIL

On-line version ISSN 1699-714XPrint version ISSN 1131-9429

Abstract

SCOLARI, MJ; BYRO, PS; APESTEGUI, MJ  and  PRIMERANO, FA. Clinical and economic evaluation of pharmaceutical interventions in a community hospital. Rev. OFIL·ILAPHAR [online]. 2022, vol.32, n.1, pp.43-49.  Epub Nov 21, 2022. ISSN 1699-714X.  https://dx.doi.org/10.4321/s1699-714x2022000100008.

Objective:

To quantify, evaluate and interpret the pharmaceutical interventions carried out by the clinical pharmacy team from a clinical and economic perspective in areas of clinical-segurical and critical care for adults and in the pediatric area of a community hospital.

Methods:

Retrospective, observational and cross-sectional study lasting 6 months. Pharmaceutical interventions were classified according to their problems related to drugs and their clinical relevance as potentially lethal, serious, significant and non-significant. The excess in stay potentially prevented by the intervention was also determined. Considering all this clinical edge, we estimated the unified cost potentially avoided, in the study period, to determine the economic impact. A subgroup analysis was performed to compare the clinical and economic impact corresponding to each section considered.

Results:

2,442 pharmaceutical interventions were analyzed corresponding to a total of 1,156 patients. The most frequent interventions were those related to the indicated doses. According to severity, most of interventions were classified as significant, having avoided, on average, 2.67% of excess in stay. Acceptance was 95%. An unified potentially avoided cost of over 13 million Argentine pesos was calculated during the study period.

Conclusions:

A favorable clinical and economic impact related to the interventions was observed, both globally and in the subpopulations of patients in each section.

Keywords : Pharmaceutical intervention; pharmacotherapeutic follow-up; clinical pharmacy; clinical impact; economic impact.

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