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Revista de la OFIL

On-line version ISSN 1699-714XPrint version ISSN 1131-9429

Abstract

DA SILVA, AL et al. Evaluation instruments of peripheral neuropathy induced by chemotherapy in patients with multiple myeloma. Rev. OFIL·ILAPHAR [online]. 2022, vol.32, n.4, pp.387-393.  Epub Oct 23, 2023. ISSN 1699-714X.  https://dx.doi.org/10.4321/s1699-714x20220004000012.

Objective:

To identify instruments for evaluation of peripheral neuropathy induced by chemotherapy that can be translated or adapted to monitor this adverse drug reaction in patients with multiple myeloma.

Method:

Narrative review, conducted between July 2018 and may 2019. Articles published in English and Portuguese were eligible between June2007 and January 2019, available in full in a free manner or in periodicals of the CAPES Coordination Portal for Improvement of Level Personnel Higher. Animal studies, monographs, guidelines, theses, clinical cases and non-health studies were excluded.

Results:

Five instruments were identified:Patient Neurotoxicity Questionnaire;Funcional Assessment of Cancer Therapy/Gynecologyc Group – Neurotoxicity;Chemotherapy-Induced Peripheral NeuropathyAssessment Tool; Funcional AssessmentCancer Therapy/Taxane; Indicationfor Common Toxicity Criteria – Grading ofPeripheral Neuropathy Questionnaire (ICPNQ). After analyzing each tool presented,the ICPNQ proved to be valid andapplicable in clinical practice, however, itis in the English language.

Conclusion:

The translation and validation of the ICPNQ instrument into Portuguese would allow its incorporation into clinical practice in the monitoring of peripheral neuropathy induced by chemotherapy in patients with multiple myeloma.

Keywords : Drug-related side effects and adverse reactions; antineoplastic agents; drug therapy; peripheral nervous system diseases; hematologic diseases.

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