Objective:

The aim of our study is to calculate the indicators of hospital use of antimicrobial agents based on consumption, comparing data from 2018 with data from 2019 in an Intensive Care Unit of a third level hospital without an stewardship program.

Methods:

Retrospective study in which we assigned a value to each indicator based on consumption using DDD per 100 bed-stays. Data was obtained using the pharmacy management software. Statistical analysis was performed by t-Student test based on the difference of means obtained in 2018 and 2019 respectively.

Results:

13 indicators were evaluated, only 2 of them (15%) showed an statistically significant difference between periods, the consumption of fluoroquinolones and the fluconazole/ echinocandin ratio, both showing a positive evolution.

Conclusions:

The use of these indicators should be standardized in order to evaluate antibiotic policies, which will help establishing comparisons between centers of specific characteristics or studying the temporal evolution for the same center and/or service. This will allow detecting critical points and establishing improvement actions, including the creation of stewardship programs, especially in critical care units.

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