Abstract

RODRIGO CALDUCH, Teresa. Publication bias and non-reproducibility in the ethical balance of animal research projects. Rev. Bioética y Derecho [online]. 2021, n.51, pp.61-79.  Epub Mar 29, 2021. ISSN 1886-5887.

Regulations governing animal research establish approval of research projects after having undergone a proper ethical harm-benefit assessment. Publication bias and lack of reproducibility in animal research undermine the proper ethical balance of projects. It is necessary to promote measures involving all participants (scientists, editorial groups, governmental and funder's agencies) to generate changes in the scientific culture in order to revalue negative results as part of general scientific knowledge and to increase quality of reports.

Keywords : animal research; ethical balance; publication bias; negative results; crisis of reproducibility.

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