Abstract

HEREDIA ANTUNEZ, Anayántzin Paulina; VANDA CANTON, Beatriz  and  SANTILLAN-DOHERTY, Patricio. Challenges for Ethic Committees in Animal Research. Mexican experience. Rev. Bioética y Derecho [online]. 2021, n.51, pp.99-121.  Epub Mar 29, 2021. ISSN 1886-5887.

The approval of the use of animals in biomedical research projects depends on the ethics committees for the care and use of laboratory animals, who must evaluate ethical and methodological aspects of the projects that are carried out and are intended to ensure the proper management and use of animals, from obtaining to death based on current scientific knowledge, risk-benefit analysis, the implementation of the three R's (3R's) applied to replacement, reduction and refinement, and the criteria of animal welfare science. Attention to each stage of project design and evaluation is often underestimated by both scientists and committee members, who must take responsibility for reducing pain and discomfort to animals throughout the investigation. On the other hand, some of the limitations that these committees face in carrying out their work and ensuring that animals are used are exposed as long as it is justified.

Keywords : IACUC; ethics in research; risk-benefit analysis; animal welfare; animal research.

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